What do I have to know or not to see if your new medicine works
is this sentence correct or make sense should there be a comma after not? wouldn't it be better to write it this way "what do I have to know or not know, in order to see if your new medication works?" or maybe there is no comma after "know" in the second sentence?
2 answers 
I would leave out the 'not know' part. There is nothing that the lack of knowledge could add to establishing the drug's benefit.
What do I have to know to see if your new medicine works?
A more clear question would be:
What do I look for to tell if the medicine is working?
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answered Jan 31 at 18:16
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"What do I have to know or not know in order to see if your new medication works?"
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edited Jan 31 at 17:22
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